发明名称 |
CONTROLLED RELEASE SOLID PREPARATION |
摘要 |
<p>Disclosed is a solid preparation which comprises at least one active ingredient and at least one dissolution-controlling base substance and can be formed by compression molding, wherein the dissolution-controlling base substance contains 5.0 to 99.9% by weight (inclusive) of a modified starch having a moisture retaining capacity of 400% or more and a gel indentation load of 200 g or more, containing a water-soluble ingredient in an amount of 40 to 95% by weight, having particles passing through a 75 µm-mesh sieve in the proportion of 90% by weight or more and particles passing through a 32 µm-mesh sieve in the proportion of 20% by weight or more, and having an average particle diameter of not smaller than 20 µm and smaller than 50 µm.</p> |
申请公布号 |
EP1946780(B1) |
申请公布日期 |
2012.01.11 |
申请号 |
EP20060823309 |
申请日期 |
2006.11.10 |
申请人 |
ASAHI KASEI CHEMICALS CORPORATION |
发明人 |
ENDO, MASAAKI;OBAE, KAZUHIRO;IBUKI, ICHIROU;YAGINUMA, YOSHIHITO |
分类号 |
A61K47/36;A61K9/20;A61K9/24;A61K9/36;A61K47/04;A61K47/10;A61K47/26;A61K47/34 |
主分类号 |
A61K47/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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