COMPOSITION FOR INJECTION COMPRISING DOCETAXEL AND PREPARATION METHOD THEREOF
摘要
<p>A composition for injection comprising docetaxel and polysorbate 80, wherein the mass ratio between docetaxel and polysorbate 80 is 1 : 26.75. The preparation method of the composition is as follows: 1) formulating the stock solution by adding polysorbate 80 to a tank and then adding absolute ethanol slowly with stirring until the density of the stock solution being 0.886~0.896g/ml; 2) dissolving docetaxel in the stock solution; 3) the resulted solution being filtered and distributed in sterile condition and then vacuum drying to remove the ethanol.</p>