MULTIFUNCTIONAL COPOLYMERS FOR NUCLEIC ACID DELIVERY
摘要
The present invention relates to multifunctional polymers represented by the following formula: The invention further provides methods for their preparation and methods for site- specific delivery of nucleic acids by combining them with targeting ligands, endosomolytic ligands and/or PK modulator ligands.
申请公布号
WO2011163121(A1)
申请公布日期
2011.12.29
申请号
WO2011US41062
申请日期
2011.06.20
申请人
ALNYLAM PHARMACEUTICALS, INC.;MANOHARAN, MUTHIAH;RAJEEV, KALLANTHOTTATHIL, G.
