发明名称 FLUORESCENT PROBE FOR USE IN MEASUREMENT OF PROTEASE
摘要 <p>A compound represented by the formula (I) or a salt thereof (R 1 represents hydrogen atom, or a substituent; R 2 to R 7 represent hydrogen atom, hydroxyl group, an alkyl group, or a halogen atom; R 8 and R 9 represent hydrogen atom, or an alkyl group; X represents a C 1 -C 3 alkylene group; and R 10 represents an acyl group), which promptly causes a structural change from a non-fluorescent closed ring structure to a strongly fluorescent open ring structure by hydrolysis of an acyl group, and is useful as a fluorescent probe for measuring a protease showing superior suitability for quantification.</p>
申请公布号 EP2399920(A1) 申请公布日期 2011.12.28
申请号 EP20100743579 申请日期 2010.02.19
申请人 THE UNIVERSITY OF TOKYO 发明人 NAGANO, TETSUO;URANO, YASUTERU;SAKABE, MASAYO
分类号 C07D493/10;G01N21/78 主分类号 C07D493/10
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