| 发明名称 |
AGONISTS AND ANTAGONISTS OF THE SIP5 RECEPTOR, AND METHODS OF USES THEREOF |
| 摘要 |
<p>Disclosed are compounds that are agonists or antagonists of the S1P5 receptor, compositions comprising said compounds, and methods of using said compounds and compositions. In certain embodiments, said compounds are 1-benzylazetidine-3-carboxylic acid derivatives. In certain embodiments, said methods relate to the treatment of neuropatic pain and/or a neurodegenerative disorder. In certain embodiments, said compounds may be used in combination with a second therapeutic agent.</p> |
| 申请公布号 |
EP2395835(A1) |
申请公布日期 |
2011.12.21 |
| 申请号 |
EP20100741670 |
申请日期 |
2010.02.10 |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
HARRIS, CHRISTOPHER, M.;HOBSON, ADRIAN, D.;WILSON, NOEL, S. |
| 分类号 |
A61P37/00;A61K31/33;C07D207/08;C07D207/16;C07D209/52;C07D211/60;C07D211/62;C07D213/64;C07D239/42;C07D307/22;C07D401/06;C07D401/10;C07D403/06;C07D409/06;C07D409/10;C07D409/12;C07D413/06;C07D417/06 |
主分类号 |
A61P37/00 |
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