发明名称 Pyrrolidine ether derivatives as NK3 receptor antagonists
摘要 The present invention relates to compounds of formula I wherein R1, R2, R3, R′, Ar, m, n, and o are as defined herein. The invention also relates to pharmaceutical compositions containing compounds of formula I and methods for the manufacture of such compounds and compositions. Compounds of the invention are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
申请公布号 US8063075(B2) 申请公布日期 2011.11.22
申请号 US20090476267 申请日期 2009.06.02
申请人 JABLONSKI PHILIPPE;KAWASAKI KENICHI;KNUST HENNER;LIMBERG ANJA;NETTEKOVEN MATTHIAS;RATNI HASANE;RIEMER CLAUS;HOFFMANN-LA ROCHE INC. 发明人 JABLONSKI PHILIPPE;KAWASAKI KENICHI;KNUST HENNER;LIMBERG ANJA;NETTEKOVEN MATTHIAS;RATNI HASANE;RIEMER CLAUS
分类号 A61K31/40;A61K31/44;C07D207/04;C07D401/06 主分类号 A61K31/40
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