发明名称 |
TETRAPEPTIDE REGULATING BLOOD GLUCOSE LEVEL IN DIABETES MELLITUS |
摘要 |
The invention refers to the field of medicine and can be applied as a substance capable of regulating glucose level while treating and preventing diabetes mellitus. There is proposed a biologically active new tetrapeptide lysyl-glutamyl-aspartyl-tryptophane of general formula Lys-Glu-Asp-Trp-NH2 capable of regulating the glucose level, and pharmacological substance containing an effective amount of tetrapeptide lysyl-glutamyl-aspartyl-tryptophane of the general formula Lys-Glu-Asp-Trp-NH2. There is proposed the method of prevention and/or treatment of the diabetes mellitus, which consists in administering to a patient of the pharmacological substance, containing as an active peptide agent an effective amount of Lys-Glu-Asp-Trp-NH2 tetrapeptide in doses of 0,1 - 30 ~g/kg of the body weight at least once a day for a period necessary for attaining a therapeutic effect.
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申请公布号 |
CA2547873(C) |
申请公布日期 |
2011.11.22 |
申请号 |
CA20042547873 |
申请日期 |
2004.08.09 |
申请人 |
SANKT-PETERBURGSKAYA OBSCHESTVENNAYA ORGANIZATSIYA "SANKT-PETERBURGSKIY INSTITUT BIOREGULYATSII I GERONTOLOGII SZO RAMN" |
发明人 |
KHAVINSON, VLADIMIR KHATSKELEVICH;MALININ, VLADIMIR VIKTOROVICH;GRIGORIEV, EVGENY IOSIFOVICH;RYZHAK, GALINA ANATOLIEVNA |
分类号 |
A61K38/07;C07K5/10;A61K38/00;A61P3/10;C07K5/11 |
主分类号 |
A61K38/07 |
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