COLLAGEN GEL FOR BONDING POROUS COLLAGEN- BASED MATERIALS WITH NON- POROUS COLLAGEN- BASED MATERIALS

摘要

The invention discloses a process for fabricating a biomaterial, comprising: a) joining a porous collagen based-material with a non-porous collagen based- material by applying a controlled amount of a bonding layer of a gel comprising collagen to a bonding surface of the non-porous collagen based-material, and contacting a surface of the porous collagen based-material with the gel applied to the bonding surface to partially hydrate a section of the porous material at the interface between the materials; b)drying the gel to dry to bond the materials together; and c)cross-linking the collagens in the bonding layer. Also disclosed are biomaterials and implants produced using the fabrication process.