| 发明名称 |
CARBAMIC ACID COMPOUNDS COMPRISING A PIPERAZINE LINKAGE AS HDAC INHIBITORS |
| 摘要 |
This invention pertains to certain carbamic acid compounds which inhibit HDAC (histone deacetylase) activity of the following formula: The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HDAC, and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, etc.
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| 申请公布号 |
US2011275810(A1) |
申请公布日期 |
2011.11.10 |
| 申请号 |
US201113184869 |
申请日期 |
2011.07.18 |
| 申请人 |
WATKINS CLARE J;ROMERO-MARTIN MARIA-ROSARIO;RITCHIE JAMES;FINN PAUL W;KALVINSH IVARS;LOZA EINARS;DIKOVSKA KLARA;STARCHENKOV IGOR;LOLYA DAINA;GAILITE VIJA |
发明人 |
WATKINS CLARE J.;ROMERO-MARTIN MARIA-ROSARIO;RITCHIE JAMES;FINN PAUL W.;KALVINSH IVARS;LOZA EINARS;DIKOVSKA KLARA;STARCHENKOV IGOR;LOLYA DAINA;GAILITE VIJA |
| 分类号 |
C07D295/16;C07D295/26;A61K31/495;A61K31/496;A61K31/506;A61P17/06;A61P35/00;A61P43/00;C07D209/14;C07D209/16;C07D209/18;C07D209/42;C07D213/36;C07D213/74;C07D239/42;C07D241/04;C07D295/18;C07D295/185;C07D295/192;C07D295/22;C07D317/58;C07D333/60;C07D401/04;C07D403/04;C07D405/10 |
主分类号 |
C07D295/16 |
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