发明名称 |
DETERMINATION OF COMPLEX PHOSPHOLIPID/LIPID STRUCTURES WITH THE AID OF SYNTHETIC FLUORESCENCE-LABELED ACYLGLYCERIDES |
摘要 |
Test for determination of the integrity of complex phospholipid/lipid structures with the aid of synthetic fluorescence-labeled acylglycerides and its use for determination of the activity of lipases/lipase inhibitors. A simple continuous test for the identification of structures which favor the arrangement of aromatics to give charge-transfer complexes, such as, for example, complex phospholipid/lipid structures (bilayer, monolayer, aggregate, micelles), with the aid of synthetic fluorescence-labeled acylglycerides, and its use for determination of the activity of lipases/lipase inhibitors, is described, furthermore a monoacylglyceride for use in this test and a process for its preparation, and the substrate obtained therefrom and a process for the preparation thereof.
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申请公布号 |
CA2384394(C) |
申请公布日期 |
2011.11.08 |
申请号 |
CA20002384394 |
申请日期 |
2000.04.13 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
MUELLER, GUENTER;PETRY, STEFAN;JORDAN, HOLGER;KLEINE, HORST;WENZEL, HORST |
分类号 |
G01N33/92;A61P43/00;C07D271/08;C07D271/12;C12N9/16;C12N9/99;C12Q1/02;C12Q1/34;C12Q1/44;G01N21/78;G01N33/15;G01N33/50;G01N33/58;G01N33/68 |
主分类号 |
G01N33/92 |
代理机构 |
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地址 |
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