INTERMEDIATES FOR THE PREPARATION OF HMG-COA REDUCTASE INHIBITORS AND PROCESSES FOR THE PREPARATION THEREOF

摘要

A compound of general Formula (1), is disclosed wherein P1 and P2 are alcohol protecting groups or 1,3-diol protecting group, R is: (a) or (b) or (c) wherein R4a is alkyl, aryl, arylalkyl or cycloalkyl, Rc is H, alkyl, aryl, alkaoxy, haloalkyl, monohaloalkyloxy, dihaloalkyloxy, Rd is alkyl, aryl, arylalkyl, CF3, halo or NO2 and X is O, N-H, N-alkyl or S, Ra and Rb may be same or different and each represents hydrogen, an alkyl group of 1 to 12 carbon atoms, an aryl group of 6 to 12 carbon atoms, or an aralkyl group of 7 to 12 carbon atoms.