PROPHYLACTIC OR THERAPEUTIC AGENT FOR DISEASES ASSOCIATED WITH ABNORMAL BONE METABOLISM

摘要

PURPOSE: An agent for preventing or treating diseases caused by bone metabolic abnormality using N-hydroxybenzamidine derivatives or salt thereof is provided. CONSTITUTION: An agent for preventing or treating diseases caused by bone metabolic abnormality contains N-hydroxybenzamidine derivatives of formula I or salt thereof; and active vitamin D or prodrug thereof as an active ingredient. The N-hydroxybenzamidine derivative of formula I is N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazole-4-yl)phenoxy]pentoxy}benzamidine.