CONFORMATIONALLY RESTRICTED DINUCLEOTIDE MONOMERS AND OLIGONUCLEOTIDES
摘要
This invention relates to conformationally locked dinucleotide motifs for exo- and phosphate stabilization. For instance, oligonucleotides can be prepared having one or more of the following formulas (IV-IX).
申请公布号
WO2011133868(A2)
申请公布日期
2011.10.27
申请号
WO2011US33588
申请日期
2011.04.22
申请人
ALNYLAM PHARMACEUTICALS, INC.;MANOHARAN, MUTHIAH;LACKEY, JEREMY;RAJEEV, KALLANTHOTTATHIL, G.;ZLATEV, IVAN
发明人
MANOHARAN, MUTHIAH;LACKEY, JEREMY;RAJEEV, KALLANTHOTTATHIL, G.;ZLATEV, IVAN
