Tracers for imaging distribution of reactive oxygen species (ROS) are disclosed. The tracers include radiolabeled dihydroethidine (DHE) analogues. Further disclosed are uses of the compounds, including methods of imaging tissue distribution of ROS in vivo by positron emission tomography (PET). Methods of synthesizing the compounds are also disclosed.
申请公布号
WO2011084585(A3)
申请公布日期
2011.10.13
申请号
WO2010US60735
申请日期
2010.12.16
申请人
WASHINGTON UNIVERSITY;MACH, ROBERT;MINTUN, MARK;CHU, WENHUA;DUGAN, LAURA
发明人
MACH, ROBERT;MINTUN, MARK;CHU, WENHUA;DUGAN, LAURA