发明名称 |
PROLIFERATION-ASSOCIATED MODULATION OF THE SPLICING OF THE INTEGRIN ALPHA 6 ISOFORMS |
摘要 |
<p>This application relates to the use of agents such as expression vectors and nucleic acids encoding integrins α6A or α6B as well as antibodies specific for those integrins which are capable of modulating the ratio between the B and A isoforms of the α6 integrin in the treatment of diseases associated with an altered proliferation rate, such as cancer. The application also relates to the use of the ratio between the B and A isoforms of the α6 integrin in the diagnosis of diseases associated with an altered proliferation rate.</p> |
申请公布号 |
EP2370109(A1) |
申请公布日期 |
2011.10.05 |
申请号 |
EP20090831355 |
申请日期 |
2009.12.10 |
申请人 |
SOCPRA SCIENCES SANTE ET HUMAINES S.E.C. |
发明人 |
BEAULIEU, JEAN-FRANCOIS;HERRING, ELIZABETH;BASORA, NURIA;GROULX, JEAN-FRANCOIS |
分类号 |
A61K31/7088;A61K38/17;A61P35/00;C12N15/113;C12Q1/68;G01N33/574;G01N33/68 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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