发明名称 |
Modulation of Glucocorticoid Receptor Expression |
摘要 |
<p>Compounds, compositions and methods are provided for modulating the expression of glucocorticoid receptor. The compositions comprise antisense compounds, particularly antisense oligonucleotides which have particular in vivo properties, targeted to nucleic acids encoding glucocorticoid receptor. Methods of using these compounds for modulation of glucocorticoid receptor expression and for treatment of diseases are provided.</p> |
申请公布号 |
EP2368988(A1) |
申请公布日期 |
2011.09.28 |
申请号 |
EP20110152132 |
申请日期 |
2006.09.19 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MONIA, BRETT P.;MCKAY, ROBERT;FREIER, SUSAN M.;BHANOT, SANJAY;WATTS, LYNNETTA |
分类号 |
A61K31/7088;A61K38/00;A61P3/00;C07H21/00;C12N15/113 |
主分类号 |
A61K31/7088 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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