摘要 |
The present invention relates to a patch which is free from any migration of a drug into a substrate and has favorable anchoring properties between the substrate and a adhesive layer, in which the drug-containing adhesive layer firmly adheres onto the substrate and which gives no adhesive residue when applied to the skin and then peeled off. Namely, a patch comprising a substrate made of a polyester-based film and a drug-containing adhesive layer laminated thereon wherein the surface roughness of the polyester-based film surface in the side in contact with the adhesive layer is from 0.05 to 0.8 mu mRa is provided. |