发明名称 PROTEASE-RESISTANT MUTANTS OF STROMAL CELL DERIVED FACTOR-1 IN THE REPAIR OF TISSUE DAMAGE
摘要 The present invention features mutant stromal cell derived factor-1 (SDF-1) peptides that have been mutated to make them resistant to digestion by, for example, the proteases dipeptidyl peptidase IV (DPPIV), matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), leukocyte elastase, cathepsin G, carboxypeptidase M, and carboxypeptidase N, but which retain chemoattractant activity.
申请公布号 US2011224139(A1) 申请公布日期 2011.09.15
申请号 US201113029891 申请日期 2011.02.17
申请人 PROVASCULON, INC. 发明人 SEGERS VINCENT FRANS MARIA;SANDRASAGRA ANTHONY;QIU YAN
分类号 A61K38/18;A61P9/10;A61P17/02;C07H21/04;C07K7/06;C07K7/08;C07K14/475 主分类号 A61K38/18
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