METHODS AND COMPOSITIONS FOR IMPROVING EFFICIENCY OF NUCLEIC ACIDS AMPLIFICATION REACTIONS
摘要
The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonuclease activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.
申请公布号
SG172925(A1)
申请公布日期
2011.08.29
申请号
SG20110050093
申请日期
2010.01.07
申请人
BIO-RAD LABORATORIES, INC.
发明人
GONG, XIAO-SONG;SULLIVAN, JOHN;FU, RONGDIAN;WANG, YAN;BURSEY, EVAN, H.;CHENG, MAN