| 摘要 |
THE COMPOUNDS OF THE SUBJECT INVENTION HAVE A STRUCTURE ACCORDING TO FORMULA &Igr; : WHEREIN X IS S OR S0₂; R¹ IS (1C-6C)ALKYL, (3C-6C)ALKENYL, OR (3C-6C)ALKYNYL, EACH OPTIONALLY SUBSTITUTED WITH (3C-6C)CYCLOALKYL, OH, OC(O)(1C-4C)ALKYL, (1C- 4C)ALKOXY, HALOGEN, CYANO, FORMYL, C(O)(1C-4C)ALKYL, CO₂H, C0₂(1C- 4C)ALKYL, C(O)NR⁵R⁶, S(O)₂(1C-4C)ALKYL; OR S(O)₂(1C-4C)ALKYL; R² IS HYDROGEN, (1C-4C)AKYL OR C(O)(1C-4C)ALKYL; IS R³ IS A PHENYL GROUP OPTIONALLY SUBSTITUTED WITH (1C-4C)ALKYL, (1C- 4C)FLUOROALKYL, (1C-4C)ALKOXY, (1C-4C)FLUOROALKOXY, HALOGEN, CYANO OR NITRO; OR R³ IS A 5-OR 6-MEMBERED AROMATIC HETEROCYCLIC RING STRUCTURE OPTIONALLY SUBSTITUTED WITH (1C-4C)ALKYL, (1C-4C)FLUOROALKYL, (1C-4C)ALKOXY, HALOGEN OR CYANO;R⁴ IS A PHENYL GROUP OR AN AROMATIC 6-MEMBERED HETEROCYCLE, SUBSTITUTED AT THE ORTHO POSITION WITH 1-HYDROXY(1C-4C)ALKYL, (1C-4C)ALKOXY, C(O)(1C- 4C)ALKYL, CO₂(1C-4C)ALKYL, C(O)NH₂, CYANO, NITRO, OR CH=NOR⁷, AND OPTIONALLY FURTHER SUBSTITUTED WITH (1C-2C)ALKYL, (1C-2C)FLUOROALKYL OR HALOGEN; OR R⁴ IS 2-PYRIDYL OPTIONALLY SUBSTITUTED WITH (1C-2C)ALKYL, (1C- 2C) FLUOROALKYL OR HALOGEN; R⁵ AND R⁶ ARE INDEPENDENTLY HYDROGEN OR (1C-4C)ALKYL; R⁷ IS HYDROGEN OR C(O)(1C-4C)ALKYL; R⁸, R⁹, R¹⁰ ARE INDEPENDENTLY HYDROGEN, (1C-2C)ALKYL, FLUORO OR CHLORO; OR A SALT OR HYDRATE FORM THEREOF.
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