PEPTIDES CAPABLE OF INHIBITING THE INTERACTION BETWEEN PRESENILINS AND THE BETA-AMYLOID PEPTIDE OR ITS PRECURSOR

摘要

The invention concerns novel peptide and nucleotide sequences, and their pharmaceutical use. More particularly, the invention concerns novel polypeptides capable of inhibiting at least partially the interaction between presenilin 1 or presenilin 2 and the beta -amyloid peptide precursor and/or the beta -amyloid peptide. The invention also concerns the preparation of in vitro tests for detecting molecules and in particular molecules capable of inhibiting said interaction.