| 发明名称 |
BOTULINUS TOXIN FORMULATION CAPABLE OF HIGH-DOSE ADMINISTRATION |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a botulinus toxin formulation capable of extremely safer high-dose administration than existing botulinus toxin A-type formulation. SOLUTION: This invention relates to a botulinus toxin type-C<SB>1</SB>, D, E or F formulation extremely wider in therapeutic range than existing botulinus toxin type-A formulation and capable of safely administrating much more effective amount. For example, botulinus toxin type-C<SB>1</SB>can be safely administered to a total of about 1,925 U/kg body weight, and the effect is equivalent to about 250 U/kg body weight in terms of botulinus toxin type-A formulation. COPYRIGHT: (C)2011,JPO&INPIT |
| 申请公布号 |
JP2011157331(A) |
申请公布日期 |
2011.08.18 |
| 申请号 |
JP20100022569 |
申请日期 |
2010.02.03 |
| 申请人 |
CHEMO-SERO-THERAPEUTIC RESEARCH INST |
发明人 |
TORII KYOJI;GINNAGA AKIHIRO;NAKAHIRA SHINJI;HARAKAWA TETSUHIRO;OYAMA YUSUKE;NAGANO AKITAKA;GOTO TSUYOTAKA;SHINMURA MIHO;MUNECHIKA SATOMI;HARADA KAORI;ITAI SHIHO;KAJI TATSUJI;OZAKI SHUNJI |
| 分类号 |
A61K38/00;A61K47/16;A61K47/42;A61P1/00;A61P1/04;A61P1/08;A61P1/18;A61P3/10;A61P5/00;A61P5/14;A61P9/10;A61P13/00;A61P13/08;A61P15/00;A61P17/00;A61P17/14;A61P19/00;A61P19/02;A61P21/00;A61P25/00;A61P25/02;A61P25/04;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P35/00 |
主分类号 |
A61K38/00 |
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