| 发明名称 |
CHIMERIC SMALL MOLECULES FOR THE RECRUITMENT OF ANTIBODIES TO CANCER CELLS |
| 摘要 |
The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
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| 申请公布号 |
US2011201563(A1) |
申请公布日期 |
2011.08.18 |
| 申请号 |
US20090991926 |
申请日期 |
2009.05.13 |
| 申请人 |
YALE UNIVERSITY |
发明人 |
SPIEGEL DAVID;MURELLI RYAN;ZHANG ANDREW |
| 分类号 |
A61K31/702;A61K31/195;A61K31/4192;A61K31/66;A61K31/675;A61P35/00;A61P35/02;C07C321/00;C07D249/04;C07D403/14;C07F9/28;C07H99/00 |
主分类号 |
A61K31/702 |
| 代理机构 |
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