发明名称 |
AROMATIC RING FUSED PYRIMIDINE DERIVATIVE |
摘要 |
A novel pyrimidine derivative in which pyrimidine has been fused with an aromatic heterocycle selected among thiophene, thiazole, and pyridine or a pharmaceutically acceptable salt of the derivative; and a medicinal composition containing the compound or salt as an active ingredient. These compounds have excellent activity in accelerating insulin secretion and excellent activity in inhibiting the increase of a blood sugar level. Therefore, the medicinal composition containing the compound or salt as an active ingredient is useful, based on these activities, for the treatment and/or prevention of insulin-dependent diabetes mellitus (type 1 diabetes), noninsulin-dependent diabetes mellitus (type 2 diabetes), insulin-resistant diseases, and obesity.
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申请公布号 |
CA2583259(C) |
申请公布日期 |
2011.08.02 |
申请号 |
CA20052583259 |
申请日期 |
2005.10.05 |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
YONETOKU, YASUHIRO;NEGORO, KENJI;ONDA, KENICHI;HAYAKAWA, MASAHIKO;SASUGA, DAISUKE;NIGAWARA, TAKAHIRO;IIKUBO, KAZUHIKO;MORITOMO, HIROYUKI;YOSHIDA, SHIGERU;OHISHI, TAKAHIDE |
分类号 |
C07D495/04;A61K31/519;A61P3/10;A61P5/50;C07D471/04;C07D513/04 |
主分类号 |
C07D495/04 |
代理机构 |
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