发明名称 |
NOVEL 6,6A,7,8,9,10-HEXAHYDRO-4H-4,8,10A-TRIAZA-ACEPHENANTHRYLENE DERIVATIVES AS DOPAMINE D2 LIGANDS |
摘要 |
This invention is directed to compounds, which are dopamine D2 ligands. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I or formula II, or a pharmaceutically acceptable salt thereof. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I or formula II, or a pharmaceutically acceptable salt thereof. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I or formula II, or a pharmaceutically acceptable salt thereof. |
申请公布号 |
WO2011088838(A1) |
申请公布日期 |
2011.07.28 |
申请号 |
WO2011DK50020 |
申请日期 |
2011.01.24 |
申请人 |
H. LUNDBECK A/S;KEHLER, JAN;KROGSGAARD-LARSEN, NIELS |
发明人 |
KEHLER, JAN;KROGSGAARD-LARSEN, NIELS |
分类号 |
C07D471/16;A61K31/4375;A61P25/00 |
主分类号 |
C07D471/16 |
代理机构 |
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地址 |
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