Described herein are novel methods of preparing a compound of Formula II or a pharmaceutically acceptable salt thereof. In some embodiments, the method is for preparing betrixaban or a pharmaceutically acceptable salt thereof. Also described are compositions comprising substantially pure betrixaban free base or salt thereof.
申请公布号
CA2784904(A1)
申请公布日期
2011.07.14
申请号
CA20102784904
申请日期
2010.12.15
申请人
MILLENNIUM PHARMACEUTICALS, INC.;PORTOLA PHARMACEUTICALS, INC.
发明人
PANDEY, ANJALI;LEITAO, EMILIA P. T.;RATO, JOSE;SONG, ZHIGUO JAKE