METHODS

摘要

The present invention provides methods for selecting an appropriate treatment regime for an individual who has been determined to have primary cancer with invasive characteristics or metastatic cancer. The invention further provides methods for selecting an appropriate treatment regime for an individual with breast cancer whose cancer has been determined to have a negative estrogen receptor a (ERa) status. The invention further provides methods for assessing the potential outcome of a cancer in such individuals. The methods, uses and means of the invention comprise assessing the level of nicastrin nucleic acid and/or protein in a sample from the individual.