发明名称 LIPIDATED IMIDAZOQUINOLINE DERIVATIVES
摘要 The compounds of the subject invention are adjuvant molecules that comprise an imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens.
申请公布号 KR20110077004(A) 申请公布日期 2011.07.06
申请号 KR20117011672 申请日期 2009.10.23
申请人 GLAXOSMITHKLINE BIOLOGICALS S.A. 发明人 JOHNSON DAVID
分类号 C07D487/04;A61K31/4745;A61P29/00 主分类号 C07D487/04
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