发明名称 |
LIPIDATED IMIDAZOQUINOLINE DERIVATIVES |
摘要 |
The compounds of the subject invention are adjuvant molecules that comprise an imidazoquinoline molecule covalently linked to a phospho- or phosphonolipid group. The compounds of the invention have been shown to be inducers of interferon-a, IL-12 and other immunostimulatory cytokines and possess an improved activity profile in comparison to known cytokine inducers when used as adjuvants for vaccine antigens. |
申请公布号 |
KR20110077004(A) |
申请公布日期 |
2011.07.06 |
申请号 |
KR20117011672 |
申请日期 |
2009.10.23 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
JOHNSON DAVID |
分类号 |
C07D487/04;A61K31/4745;A61P29/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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