发明名称 AZETIDINE POLYSUBSTITUTED COMPOUNDS, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF
摘要 The invention relates to compounds of the formula (I) where: R is a (C1-C6)alkyl group, a halo(C1-C6)alkyl group; R1 is a hydrogen atom; R2 is a heteroaromatic group or a heteroaromatic(C1-C4)alkyl group, said groups being optionally substituted; R3 and R4 represent independently from each other an optionally substituted phenyl group; Y is a hydrogen atom, a halogen, a cyano, a (C1-C6)alkyl group, a halo(C1-C6)alkyl group, a (C1-C6)alkoxy group, a halo(C1-C6)alkoxy group or a (C1-C6)alkylS(O)p group; and p is 0 to 2. Said compounds can be in the form— of a base or a salt for addition to an acid. The invention also relates to a method for preparing same and to the therapeutic application thereof.
申请公布号 US2011152236(A1) 申请公布日期 2011.06.23
申请号 US200913058913 申请日期 2009.08.13
申请人 SANOFI-AVENTIS 发明人 BERNARDELLI PATRICK;SABUCO JEAN-FRANCOIS;TERRIER CORINNE
分类号 A61K31/427;A61K31/41;A61K31/4155;A61K31/4178;A61K31/4196;A61K31/422;A61K31/4245;A61K31/433;A61K31/4427;A61K31/497;A61K31/506;A61P1/00;A61P1/04;A61P1/08;A61P1/12;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P5/00;A61P7/00;A61P9/00;A61P11/00;A61P11/06;A61P15/00;A61P19/10;A61P25/00;A61P25/04;A61P25/16;A61P25/18;A61P25/20;A61P25/28;A61P25/30;A61P25/34;A61P27/06;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P37/02;C07D401/12;C07D403/12;C07D413/12;C07D417/12 主分类号 A61K31/427
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