ENGINEERED PROTEINS INCLUDING MUTANT FIBRONECTIN DOMAINS
摘要
<p>The present invention features engineered proteins that can include a genetically modified Fn domain; two or more such domains joined to one another; or at least one genetically modified Fn domain joined to a target-specific protein scaffold. One or more accessory sequences can be included in or added to any of these configurations. Methods of use, including methods of treating cancer, with the engineered proteins are also disclosed.</p>
申请公布号
WO2011020033(A3)
申请公布日期
2011.06.23
申请号
WO2010US45490
申请日期
2010.08.13
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;WITTRUP, K., DANE;SPANGLER, JAMIE, B.;HACKEL, BENJAMIN, JOSEPH
发明人
WITTRUP, K., DANE;SPANGLER, JAMIE, B.;HACKEL, BENJAMIN, JOSEPH