发明名称 |
USE OF METFORMIN IN CANCER TREATMENT AND PREVENTION |
摘要 |
Disclosed herein is a method for treating a tumor in a subject in need thereof comprising administering an enhancing amount of metformin and a reduced amount of one or more chemotherapeutic agents. One example of an enhancing amount of metformin is about 250 mg/day. Also disclosed is a method for preventing cancer or delaying the recurrence of cancer in a subject comprising administering an effective amount of metformin to the subject. In one example of such a method, the amount of metformin is about 75 mg/day. Also disclosed is a composition comprising an enhancing amount of metformin, and a reduced amount of one or more chemotherapeutic agents and a pharmaceutically acceptable carrier. Kits comprising metformin and one or more chemotherapeutic agents are also disclosed. |
申请公布号 |
WO2011031474(A3) |
申请公布日期 |
2011.06.16 |
申请号 |
WO2010US46616 |
申请日期 |
2010.08.25 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;STRUHL, KEVIN;HIRSCH, HEATHER;ILIOPOULOS, DIMITRIOS |
发明人 |
STRUHL, KEVIN;HIRSCH, HEATHER;ILIOPOULOS, DIMITRIOS |
分类号 |
A61K31/155;A61K31/17;A61K31/33;A61P35/00 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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