METHODS AND SYSTEMS FOR TREATING AND PREVENTING CARDIAC INJURY IN DYSTROPHIC SUBJECTS

摘要

The present invention provides methods for treating and preventing cardiac deficiencies and injuries (e.g., cardiac injury and ventricular dilation) in dystrophic subjects using poloxamer containing compositions. In some embodiments, the polaxamers are administered to dystrophic subjects prior to cardiac stress, such as that caused by anaesthesia. In other embodiments, the present invention provides systems comprising poloxamer compositions and at least one anaesthetic agent.