发明名称 |
Process for the preparation of gadobenate dimeglumine complex in a solid form |
摘要 |
The present invention discloses a process for the preparation of gadobenate dimeglumine complex in a solid form. In particular, said solid form is conveniently obtained by spray-drying a corresponding liquid suspension at a given temperature and concentration. The present invention is particularly advantageous for the industrial scale as the solid form may be obtained by employing water as a solvent, which is a non-toxic solvent, easy to handle and basically not requiring troublesome health or safety precautions. |
申请公布号 |
EP2327395(A1) |
申请公布日期 |
2011.06.01 |
申请号 |
EP20090176713 |
申请日期 |
2009.11.23 |
申请人 |
BRACCO IMAGING S.P.A |
发明人 |
FRETTA, ROBERTA;FERRIGATO, AURELIA;LATTUADA, LUCIANO;MOROSINI, PIER, FRANCESCO;CERAGIOLI, SILVIA;UGGERI, FULVIO;ANELLI, PIER, LUCIO |
分类号 |
A61K9/08;A61K49/00;C07C227/38;C07C229/22 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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