发明名称 |
METHODS OF PRODUCING HUMAN RPE CELLS AND PHARMACEUTICAL PREPARATIONS OF HUMAN RPE CELLS |
摘要 |
[0362] The present invention provides improved methods for producing retinal pigmented epithelial (RPE) cells from human embryonic stem cells, human induced pluripotent stem (iPS), human adult stem cells, human hematopoietic stem cells, human fetal stem cells, human mesenchymal stem cells, human postpartum stem cells, human multipotent stem cells, or human embryonic germ cells. The RPE cells derived from embryonic stem cells are molecularly distinct from adult and fetal-derived RPE cells, and are also distinct from embryonic stem cells. The RPE cells described herein are useful for treating retinal degenerative conditions including retinal detachment and macular degeneration. |
申请公布号 |
WO2011063005(A2) |
申请公布日期 |
2011.05.26 |
申请号 |
WO2010US57056 |
申请日期 |
2010.11.17 |
申请人 |
ADVANCED CELL TECHNOLOGY, INC.;MALCUIT, CHRISTOPHER;LEMIEUX, LINDA;HOLMES, WILLIAM;HUERTAS, PEDRO;VILNER, LUCY |
发明人 |
MALCUIT, CHRISTOPHER;LEMIEUX, LINDA;HOLMES, WILLIAM;HUERTAS, PEDRO;VILNER, LUCY |
分类号 |
C12N5/071;A61K35/44;A61P27/02;C12N5/02;C12N5/0735 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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地址 |
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