发明名称 |
INNOVATIVE BLOOD PLATELETS BIOMARKER FOR EARLY DIAGNOSIS OF ALZHEIMER'S DISEASE |
摘要 |
The present invention is directed to a method for early, non-invasive, rapid, efficient, reliable and accurate diagnose of Alzheimer's disease. The present invention particularly addresses obtaining blood samples, and stabilizing platelets from healthy persons and patients with probable cognitive impairment and/or Alzheimer's disease; extracting proteins from the platelets; identifying both monomeric and oligomeric tau proteins in the platelets with at least two monoclonal antibodies against the tau proteins, quantifying the amounts of the identified tau proteins, and comparing the amounts and protein profiles of the tau molecular species in the platelets of the healthy person and the patient. |
申请公布号 |
WO2011062782(A2) |
申请公布日期 |
2011.05.26 |
申请号 |
WO2010US55623 |
申请日期 |
2010.11.05 |
申请人 |
SERVICIOS CIENTIFICOS NEUROINNOVATION LIMITADA;MACCIONI, RICARDO;FARIAS, GONZALO;LEWIN, BARRY |
发明人 |
MACCIONI, RICARDO;FARIAS, GONZALO |
分类号 |
G01N33/68;G01N33/561 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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