发明名称 |
MOLECULES INHIBITING A METABOLIC PATHWAY INVOLVING THE SYK PROTEIN TYROSINE KINASE AND METHOD FOR IDENTIFYING SAID MOLECULES |
摘要 |
The present invention relates to the C-13 molecule (methyl 2-{5-[(3-benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-benzoate) and to organic molecules functionally equivalent to the C-13 molecule, capable of inhibiting the binding of an antibody or antibody fragment with the human Syk protein tyrosine kinase, to the use of these molecules for the production of medicaments for the prevention or treatment of diseases dependent on metabolic pathways involving Syk, and also to a method for identifying such molecules.
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申请公布号 |
US2011112098(A1) |
申请公布日期 |
2011.05.12 |
申请号 |
US20090937189 |
申请日期 |
2009.04.08 |
申请人 |
DARIAVACH PIONA;MARTINEAU PIERRE EMILE ULYSSE;VILLOUTREIX BRUNO |
发明人 |
DARIAVACH PIONA;MARTINEAU PIERRE EMILE ULYSSE;VILLOUTREIX BRUNO |
分类号 |
A61K31/5377;A61K31/427;A61K31/435;A61K31/4439;A61K31/4709;A61K31/4965;A61P37/06;C07D215/227;C07D221/16;C07D241/04;C07D277/36;C07D413/06;C07D417/14 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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