发明名称 |
GLYCOSYLATED REPEAT-MOTIF-MOLECULE CONJUGATES |
摘要 |
Herein are reported glycosylated repeat-motif-molecule conjugate of the following formula: (repeat-motif-molecule - linkern)m - conjugation partner - (linkero - repeat-motif-molecule)p, wherein n and o are independently of each other and independently for each value of m and p integer values of 0 or 1, and m and p are independently of each other integer values of 0 or 1 or 2 or 3 or 4 or 5 or 6 or 7, and wherein the repeat-motif-molecule conjugate comprises at least one oligosaccharide attached to a glycosylation site. Also reported are encoding nucleic acids and method for producing these repeat-motif-conjugates in mammalian cells. |
申请公布号 |
CA2778203(A1) |
申请公布日期 |
2011.05.12 |
申请号 |
CA20102778203 |
申请日期 |
2010.11.04 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
FISCHER, STEPHAN;IMHOF-JUNG, SABINE;KOPETZKI, ERHARD |
分类号 |
C07K16/18;C07K14/47;C07K16/00;C07K16/32;C07K16/46 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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