| 发明名称 |
Alpha-(N-Sulfonamido)Acetamide Derivatives as Beta-Amyloid Inhibitors |
| 摘要 |
There is provided a series of novel α-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of &bgr;-amyloid peptide (&bgr;-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid activity.
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| 申请公布号 |
US2011105485(A1) |
申请公布日期 |
2011.05.05 |
| 申请号 |
US20100840612 |
申请日期 |
2010.07.21 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PARKER MICHAEL F.;MCELHONE KATHARINE E.;MATE ROBERT A.;BRONSON JOANNE J.;GAI YONGHUA;BERGSTROM CARL P.;MARCIN LAWRENCE R.;MACOR JOHN E. |
| 分类号 |
A61K31/541;A61K31/18;A61K31/192;A61K31/197;A61K31/216;A61K31/223;A61K31/24;A61K31/277;A61K31/341;A61K31/381;A61K31/40;A61K31/41;A61K31/415;A61K31/4164;A61K31/4184;A61K31/4196;A61K31/4245;A61K31/433;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4439;A61K31/445;A61K31/4453;A61K31/4525;A61K31/4545;A61K31/455;A61K31/47;A61K31/472;A61K31/495;A61K31/497;A61K31/5375;A61K31/5377;A61K31/54;A61P25/00;A61P25/28;A61P43/00;C07C237/04;C07C237/14;C07C311/19;C07C311/46;C07C317/32;C07C323/49;C07C323/60;C07D207/14;C07D207/32;C07D207/325;C07D211/14;C07D211/16;C07D211/28;C07D211/34;C07D211/42;C07D211/46;C07D211/58;C07D211/60;C07D213/40;C07D213/42;C07D213/61;C07D213/74;C07D213/81;C07D213/82;C07D215/06;C07D217/04;C07D217/06;C07D231/12;C07D233/61;C07D233/64;C07D235/10;C07D235/14;C07D249/08;C07D257/04;C07D261/08;C07D271/06;C07D271/10;C07D277/28;C07D285/00;C07D285/01;C07D285/06;C07D285/12;C07D295/08;C07D295/12;C07D295/13;C07D295/135;C07D295/14;C07D295/18;C07D295/20;C07D307/68;C07D333/20;C07D333/28;C07D401/04;C07D405/04;C07D413/04;C07D417/06;C07D521/00 |
主分类号 |
A61K31/541 |
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