发明名称 |
METRONOMIC CONVECTION ENHANCED DELIVERY OF INTRATHECAL CHEMOTHERAPY USING AN IMPLANTED MAGNETIC BREATHER PUMP (MBP) FOR LEPTOMENINGEAL CARCINOMATOSIS |
摘要 |
<p>A magnetically controlled pump is implanted into the cerebrospinal fluid of a patient and delivers a plurality of medicating agents at a controlled rate corresponding to the specific needs of the patient. The current invention comprises a flexible double walled lumen, intratumoral catheter which will be implanted. Spinal fluid drawn from the patient is analyzed. Medication is delivered on a continuous metronomic basis into the CSF via an internalized pump. CSF is removed and analyzed for VEGF and other cytokines via spectrophotometer analysis or a lab on a chip. The operation of the apparatus and hence the treatment is remotely controlled based on these measurements and displayed through an external controller.</p> |
申请公布号 |
CA2778277(A1) |
申请公布日期 |
2011.04.28 |
申请号 |
CA20102778277 |
申请日期 |
2010.10.19 |
申请人 |
PHARMACO-KINESIS CORPORATION |
发明人 |
SHACHAR, YEHOSHUA;CHEN, THOMAS C.;FARKAS, LESLIE;MARX, BRUCE;JOHNSON, DAVID;FARKAS, LASZLO |
分类号 |
A61F2/958;A61M1/00;A61M5/142;A61M25/088;A61M25/092;A61M31/00 |
主分类号 |
A61F2/958 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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