<p>Monoclonal antibodies that bind and inhibit activation of fibroblast growth factor receptor 3 (FGFR3) are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of FGFR3.</p>
申请公布号
EP2313435(A2)
申请公布日期
2011.04.27
申请号
EP20090774313
申请日期
2009.06.30
申请人
AVEO PHARMACEUTICALS, INC.
发明人
WENG, ZHIGANG;WINSTON, WILLIAM, M., JR.;BREAULT, LYNE;MEETZE, KRISTAN;WEILER, SOLLY;GYURIS, JENO