发明名称 Broad Spectrum Gram-Positive Antimicrobials and Anthelmintics with Efficacy Against Drug-Resistant Strains and Mycobacterium Species
摘要 The present invention provides compounds and methods of using of the compounds as anti-infective and anthelminitc agents. In a preferred embodiment, the present invention provides the following compound of Formula III: wherein: R1 is not H when R2 is H and R2 is not H when R1 is H, further wherein R1 is OH or CH(2n+1)O, wherein n is 1-10; R2 is OH or CH(2n+1)O, where n is 1-10; W is alkyl, phenyl, halophenyl, pyridyl, piperidyl, or a substituted or unsubstituted aryl group, including unsubstituted and substituted aromatic heterocycles; and L is an optional linker or linking group selected from O, S, NH, CF2, or CH2, and x=0 or 1, i.e., if x=0, no linking group is present.
申请公布号 US2011092578(A1) 申请公布日期 2011.04.21
申请号 US20100973078 申请日期 2010.12.20
申请人 MONTE AARON P;KABIR M SHAHJAHAN;ROTT MARC A;SCHWAN WILLIAM R;COOK III JAMES M;MISKOWSKI JENNIFER A 发明人 MONTE AARON P.;KABIR M. SHAHJAHAN;ROTT MARC A.;SCHWAN WILLIAM R.;COOK, III JAMES M.;MISKOWSKI JENNIFER A.
分类号 A61K31/381;A01N31/08;A01N31/14;A01N43/10;A01N43/12;A01P1/00;A01P5/00;A61K31/085;A61K31/10;A61P31/00;A61P31/04;A61P33/10;C07C43/23;C07C323/16;C07C323/18;C07D333/16;C07D333/56;C07D333/62;C07D333/64 主分类号 A61K31/381
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