发明名称 |
INHIBITOR OF ANALGESIC TOLERANCE |
摘要 |
Provided are: an agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), which comprises a compound having adenosine A 2A receptor antagonistic activity or a pharmaceutically acceptable salt thereof as an active ingredient; the agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), wherein the undesirable effect of the opioid-type analgesic (opioid) is analgesic tolerance or constipation; the agent for suppressing an undesirable effect of an opioid-type analgesic (opioid), wherein the undesirable effect of the opioid-type analgesic (opioid) is analgesic tolerance; and the like. |
申请公布号 |
EP2308509(A1) |
申请公布日期 |
2011.04.13 |
申请号 |
EP20090754797 |
申请日期 |
2009.05.29 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
OUCHI, JUN;KUNORI, SHUNJI;KOJIMA, YOZO;SHINODA, KATSUMI;SASAKI, KATSUTOSHI;SHIRAKURA, SHIRO |
分类号 |
A61K45/00;A61K31/343;A61K31/427;A61K31/4439;A61K31/506;A61K31/519;A61K31/52;A61K31/522;A61P25/04;A61P43/00;C07D417/14;C07D473/06;C07D473/34;C07D487/04;C07D487/14;C07D495/04 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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