| 摘要 |
Devices (100) for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch (100). One outer layer (110) functions as the primary adhesive layer for adhering the patch (100) to the host. The other inner layer (122) contains at least one active agent to be administered to the host. The inner layer (122) is bonded to the outer layer (110) through an opening (114) provided in an interposed active agent impermeable release layer (104). The release layer (104) separates a circumferential portion of the active agent containing inner layer (122) from the outer adhesive layer (220) to inhibit migration of the active agent therebetween. |
