| 发明名称 |
USE OF IL-18 INHIBITOR FOR THE TREATMENT AND/OR PREVENTION OF ALCOHOLIC HEPATITIS |
| 摘要 |
The invention relates to the use of IL-18 inhibitor wherein the inhibitor of IL-18 is selected from antibody against IL-18 and IL-18 binding protein, or an isoform, a mutein, fused protein, functional derivative, active fraction or circularly permutated derivative thereof having essentially the same activity as an IL-18 binding protein in the preparation of a medicament for treatment and/or prevention of alcoholic hepatitis. |
| 申请公布号 |
UA94022(C2) |
申请公布日期 |
2011.04.11 |
| 申请号 |
UA20060004789 |
申请日期 |
2001.02.20 |
| 申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;YEDA RESEARCH AND DEVELOPMENT COMPANY LTD |
发明人 |
CHVATCHKO YOLANDE;DINARELLO CHARLES;PLATER ZYBERK CHRISTINE;VAN DEVENTER SANTER;RUBINSTEIN MENACHEM;NOVICK DANIELA;KIM SOO HYUN |
| 分类号 |
A61K39/395;A61K;A61K31/00;A61K35/12;A61K38/17;A61K38/21;A61K39/35;A61K48/00;A61P;A61P1/04;A61P1/16;A61P19/02;A61P37/02;C12N;C12N15/63 |
主分类号 |
A61K39/395 |
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