Herein is reported a method for the final filtration of concentrated polypeptide solutions comprising the combination of two immediately consecutive filtration steps with a first filter of 3.0 µm and 0.8 µm pore size and a second filter of 0.45 µm and 0.22 µm pore size.
申请公布号
WO2011039274(A1)
申请公布日期
2011.04.07
申请号
WO2010EP64487
申请日期
2010.09.29
申请人
F. HOFFMANN-LA ROCHE AG;FALKENSTEIN, ROBERTO;SCHWENDNER, KLAUS
