| 发明名称 |
Acidic insulin preparations with improved stability |
| 摘要 |
<p>Composition contains (i) a polypeptide (I), i.e. insulin (bovine, porcine or human) and/or at least one of insulin analog, derivative and/or active metabolite; (ii) at least one surfactant and (iii) optionally at least one preservative, isotonicity agent, buffer and/or other auxiliaries. It is a clear solution with pH 1-6.8. ACTIVITY : Antidiabetic. No details of tests for antidiabetic activity are given. MECHANISM OF ACTION : Insulin replacement.</p> |
| 申请公布号 |
EP2305288(A2) |
申请公布日期 |
2011.04.06 |
| 申请号 |
EP20100178842 |
申请日期 |
2003.06.05 |
| 申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
BRUNNER-SCHWARZ, ANETTE;LILL, NORBERT |
| 分类号 |
A61K9/08;A61K38/28;A61K9/00;A61K45/08;A61K47/02;A61K47/04;A61K47/08;A61K47/10;A61K47/12;A61K47/14;A61K47/26;A61K47/34;A61K47/36;A61K47/42;A61P3/10 |
主分类号 |
A61K9/08 |
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