发明名称 |
SUBSTITUTED 5-PHENYLAMINO-1,3,4-OXADIAZOL-2-YLCARBONYLAMINO-4-PHENOXY-CYCLOHEXANE CARBOXYLIC ACID AS INHIBITORS OF ACETYL COENZYME A DIACYLGLYCEROL ACYLTRANSFERASE |
摘要 |
Disclosed are 5-phenylamino-1,3,4-oxadiazol-2-ylcarbonylamino-4-phenoxy-cyclohexane carboxylic acid compounds of formula (I) or a salt therof wherein the substituents are as defined in the specification, a process for preparing said compounds, and their use in inhibiting acetyl CoA (acetyl coenzyme A):diacylglycerol acyl transferase (DGAT1) and treating diabetes mellitus and or obesity.
|
申请公布号 |
NZ572586(A) |
申请公布日期 |
2011.03.31 |
申请号 |
NZ20070572586 |
申请日期 |
2007.05.29 |
申请人 |
ASTRAZENECA AB |
发明人 |
PLOWRIGHT, ALLEYN THOMAS;BUTLIN, ROGER, JOHN |
分类号 |
C07D271/10;A61K31/4245;A61P3/08;A61P3/10;A61P9/00;A61P37/02 |
主分类号 |
C07D271/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|