发明名称 Ubiquitin ligase inhibitors
摘要 This invention describes compounds useful as ubiquitin ligase inhibitors. The compounds of the invention are useful as inhibitors of the biochemical pathways of organisms in which ubiquitination is involved. The invention also provides for pharmaceutical compositions comprising the compounds described in the invention for the treatment of conditions that require inhibition of ubiquitin ligases. Furthermore, the invention provides for methods of inhibiting ubiquitination in a cell comprising contacting a cell in which inhibition of ubiquitination is desired with a compound according to the invention.
申请公布号 US7915293(B2) 申请公布日期 2011.03.29
申请号 US20040858537 申请日期 2004.06.01
申请人 RIGEL PHARMACEUTICALS, INC. 发明人 RAMESH USHA V.;LOOK GARY CHARLES;SINGH RAJINDER;ISSAKANI SARKIZ D.
分类号 A61K31/4545;C07C233/75;C07C275/34;C07C311/21;C07C311/29;C07C311/48;C07C311/51;C07C311/64;C07C317/34;C07C323/49;C07C335/42;C07D207/16;C07D207/26;C07D207/32;C07D207/325;C07D209/08;C07D211/46;C07D211/58;C07D213/42;C07D213/64;C07D213/76;C07D213/78;C07D215/40;C07D217/02;C07D231/56;C07D235/30;C07D239/34;C07D239/42;C07D261/16;C07D265/36;C07D295/13;C07D295/26;C07D307/14;C07D307/91;C07D317/66;C07D319/20;C07D333/36;C07D401/12 主分类号 A61K31/4545
代理机构 代理人
主权项
地址