| 摘要 |
Apparatus and methods in which very small volumes of biological fluid-borne material, particularly large molecules such as proteins, may be selectively extracted from or delivered to interstitial fluid (in vivo or in vitro) by means of intra-parenchymal micro-probes inserted in the brain. The primary use of the micro-probe is in neuroscience research, clinical diagnostics or treatment of epilepsy and other neurological conditions; it may also be applied to other organs and biological systems. Eventual human clinical applications may include neurosurgical monitoring, functional tracking of devices or materials introduced in a surgical procedure, or cerebro-spinal fluid sampling.
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