| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide MVA mutants, which can be used for the generation of recombinant MVA viruses, as well as host cells, which have been infected with these mutant MVA viruses. <P>SOLUTION: There are provided: a new MVA mutant in which MVA K1L gene sequences, its promoter sequences, or a functional part thereof have been inactivated in the MVA genome by mutation or deletion or both; the host cells which have been infected with these mutant MVA viruses; further, DNA-vectors constructs; and a method for the generation of recombinant MVA by using the mutant MVA viruses and the DNA-vector constructs. <P>COPYRIGHT: (C)2011,JPO&INPIT |
